Admissions 2026 ICSWHMH conference '27

Department of Biosciences

Dr. Annadurai Vinothkanna

Designation : Scientist D

Qualification : Ph.D

Email-ID : annadurai@rajagiri.edu

Dr. A. Vinothkanna is an interdisciplinary researcher specializing in microbial biotechnology, food bioscience, natural products, and bioengineering, with a strong focus on translating traditional knowledge into modern therapeutic and industrial applications. He obtained his Ph.D. in Biotechnology from Bharathidasan University, India (2019), where he investigated the probiotic potential of indigenous microbial communities from Ayurvedic fermented formulations, establishing a foundation for functional microbiome bioprospecting. He has gained extensive international research experience through postdoctoral appointments at School of Food and Biological Engineering, Jiangsu University, China (2019–2022), and School of Life and Health Sciences, Hainan University, China (2023–2025). His research integrates food science and biotechnology, focusing on probiotics from traditional fermented medicines, foods, and beverages, and the development of functional foods and nutraceuticals using probiotic consortia through fermentation and foodomics approaches. His work also examines the effects of fermented food products on gut health and metabolic disorders. Dr. Vinothkanna’s research focuses on the extraction and functional characterization of probiotic-derived bioactive compounds and postbiotics, including exopolysaccharides, peptides, and enzymes, for applications in food and health. He develops strategies to combat multidrug-resistant pathogens through quorum sensing inhibition and antibiofilm mechanisms, and designs Nano formulations for efficient bioactive delivery. His recent work integrates shotgun metagenomics, zebrafish models, and multi-scale analyses to study host–microbe interactions, biocompatibility, anti-inflammatory effects, in vivo wound healing, and toxicity mitigation. His research program combines experimental microbiology, advanced analytical techniques, and computational biology, including molecular docking, network pharmacology, and in silico modelling to understand bioactive compounds and microbial interactions. He has published 37 peer-reviewed research, review articles and 2 book chapters in reputed international journals (cumulative impact factor: 162.3; h-index up to 17) and has deposited 34 microbial strains in NCBI. He is a recipient of prestigious fellowships, including Chinese Government Postdoctoral Fellowships (2019 and 2023), the Foreign Young Talents Program (2020), China and national fellowships from the University Grants Commission, India. He actively contributes to the academic community as a reviewer for leading international journals and has served as a Guest Editor for Frontiers in Pharmacology. With over a decade of research experience, Dr. Vinothkanna’s work contributes to advancements in fermentation, functional foods, gut health, antimicrobial strategies, and sustainable biotechnological innovations.

  • Ph.D.: Biotechnology, Specialization in Microbial Biotechnology, Tiruchirappalli, Tamil Nadu, India.
  • M.Sc.: Environmental Biotechnology, Bharathidasan University, Tiruchirappalli, Tamil Nadu, India.
  • B.Sc.: Biotechnology, Tamilavel Umamaheswaranar Karanthai Arts College, Bharathidasan University, Tiruchirappalli, India.
  • Scientist -D, Division of Food Biosciences, Department of Biosciences, Rajagiri College of Social Sciences (December 2025 to till now).
  • Post-Doctoral Researcher in the School of Life and Health Sciences, Hainan University, Haikou, PR China (May 2023-May 2025).
  • Post-Doctoral Researcher in the School of Food and Biological Engineering, Jiangsu University, China (May 2019– July 2022).
  • Senior and Junior Research Fellow in the Department of Biotechnology, Bharathidasan University, India (April 2016 - February 2019).
  • University Research Fellow in Department of Biotechnology, Bharathidasan University, India (July 2013 - March 2016).
  • Probiotic characterization of native isolates from traditional fermented medicines, foods, and beverages, with emphasis on functional microbiomes.
  • Development of functional foods and nutraceuticals using probiotic strains and consortia through fermentation and foodomics approaches.
  • Investigation of fermented food systems (soybean, milk, and millets) for their role in gut health improvement and management of metabolic disorders.
  • Bioprospecting and application of postbiotics (exopolysaccharides, bioactive peptides, and enzymes) from diverse and extreme microbial resources for food bioprocessing and health applications.
  • Qi Wang*, Annadurai Vinothkanna*, Ragothaman Prathiviraj, Xia Li, Srinivasan Prabhu, Kaliyamoorthy Dass, 2026. Deciphering the Neuroprotective Potential of the Ayurvedic Ashokarishta GC-MS Derived Bioactives Through Network Pharmacology and in silico Multi-Target Analysis Against Alzheimer’s and Parkinson’s Diseases. Journal of Computational Biophysics and Chemistry. https://doi.org/10.1142/s2737416526500535. Impact Factor: 2.3
  • Annadurai Vinothkanna*, Owias Iqbal Dar, Ligang Chen, XiaoSu Ke, Sivasamy Sethupathy, Yanan Gao*, Ai-Qun Jia*, 2025. Probiotic Bacillus paramycoides and Bacillus subtilis from Chinese Shanlan rice wine inhibit biofilm formation by Burkholderia thailandensis and Staphylococcus aureus. LWT Food Science and Technology. 239,118911. Impact Factor: 6.6
  • Anwar, Muhammad, Annadurai Vinothkanna (First author equal contribution), and Aiqun Jia. 2025 Fostering plant protection against certain bacterial diseases through quorum-sensing signal molecules: A critical review. Frontiers in Plant Science 16: 1602573. Impact Factor: 4.8
  • Dar, Owias Iqbal, Annadurai Vinothkanna, Xiaosu Ke, Ligang Chen, Yanan Gao, Peng Wang, and Ai-Qun Jia., 2025. Triclosan-Mediated Metabolic Oxidative Stress-Triggered Cytoskeletal Alterations in Zebrafish Gills and Intestine: An Integrated Biomolecular and NMR-Based Metabolomics Study. Journal of Hazardous Materials: 138251. Impact Factor: 11.3
  • Tyagi, Akanksha, Yu-Yeong Choi, Lingyue Shan, Annadurai Vinothkanna, Eun-Seok Lee, Ramachandran Chelliah, Kaliyan Barathikannan et al, 2025. Limosilactobacillus reuteri fermented brown rice alleviates anxiety improves cognition and modulates gut microbiota in stressed mice. NPJ Science of Food 9: 5. Impact Factor: 7.8
  • Annadurai Vinothkanna*, Ligang Chen, Ragothaman Prathiviraj, Srinivasan Prabhu, Rekha Thiruvengadam, and Thasma Raman Sivakumar, 2025. Ashwagandharishta compounds possess affinity interactions against diabetes-linked liver cancer: Implications from network pharmacology, molecular docking and dynamics simulations. South African Journal of Botany 177: 26-49. Impact Factor: 2.7
  • Gudala, Satish, Miao Dong, Xinrui Lin, Ruotong Liu, Annadurai Vinothkanna, Anubhuti Jha, Archi Sharma, Dazhuang Wang, Xinghua Liu, and Jianxin Yang 2024. 1, 2, 4-Triazolo-quinazolinones as Effective Antifoulants: Molecular Design, Synthesis, and Biological Evaluation. Langmuir, 40(30), pp.15650-15660. Impact Factor: 3.9
  • Annadurai Vinothkanna, Xiang Shi‐Liang, Durairaj Karthick Rajan, Ragothaman Prathiviraj, Soundarapandian Sekar, Shubing Zhang, Bo Wang, Zhu Liu, and Ai‐Qun Jia, 2024. "Feasible mechanisms and therapeutic potential of food probiotics to mitigate diabetes‐associated cancers: A comprehensive review and in silico validation. Food Frontiers, 1–36.https://doi.org/10.1002/fft2.406. Impact Factor: 6.9
  • Dar, Owias Iqbal, Annadurai Vinothkanna, Bisma Aslam, Arajmand Furkh, Sunil Sharma, Arvinder Kaur, Yan-An Gao, and Ai-Qun Jia, 2024. Dynamic alterations in physiological and biochemical indicators of Cirrhinus mrigala hatchlings: A sublethal exposure of triclosan. Science of The Total Environment 924: 171701.
  • Impact Factor: 8.0
  • Kaliyan Barathikannan, Ramachandran Chelliah, Annadurai Vinothkanna, Ragothaman Prathiviraj, Akanksha Tyagi, Selvakumar Vijayalakshmi, Ai-Qun Jia and Deog- Hwan Oh, 2024. Untargeted metabolomics-based network pharmacology reveals fermented brown rice towards anti-obesity efficacy. NPJ Science of Food 8(1): 1-12.
  • Impact Factor: 7.8
  • Annadurai Vinothkanna*, Owias Iqbal Dar, Zhu Liu, and Ai-Qun Jia, 2024. Advanced detection tools in food fraud: A systematic review for holistic and rational detection method based on research and patents. Food Chemistry 446: 138893. Impact Factor: 9.8
  • Veeramuthu, Kamaraj, Vishal Ahuja, Pushparaj Annadurai, Daniel A. Gideon, Balamurugan Sundarrajan, Marius Emil Rusu, Annadurai Vinothkanna, and Kandavel Dhandayuthapani, 2023. Chemical Profiling and Biological Activity of Psydrax dicoccos Gaertn. Molecules. 28(20):7101. Impact Factor: 4.6
  • Wang Congcong, Annadurai Vinothkanna, Ma Yongkun, Hu Jie, Xue Jindong2, Li Dahai, 2023. Mulberry wine fermented by Selenium-enriched Saccharomyces cerevisiae– Sensory analysis, Phytochemical and Antioxidant activities. Journal of Food Science and Technology. Impact Factor: 3.3
  • Annadurai Vinothkanna*, Ragothaman Prathiviraj, Thasma Raman Sivakumar, Yongkun Ma, Soundarapandian Sekar, 2022. GC-MS and network pharmacology analysis of the Ayurvedic fermented medicine, Chandanasava against chronic kidney and cardiovascular diseases, Applied Biochemistry and Biotechnology. https://doi.org/10.1007/s12010-022-04242-7. Impact Factor: 3.3
  • Annadurai Vinothkanna, Krishnamurthy Mathivanan, Sivapunniyam Ananth, Yongkun Ma and Soundarapandian Sekar, 2022. Biosynthesis of copper oxide nanoparticles using Rubia cordifolia bark extract: Characterization, antibacterial, antioxidant, larvicidal and photocatalytic activities. Environmental Science and Pollution Research. https://doi.org/10.1007/s11356-022-18996-4. Impact Factor: 0
  • Annadurai Vinothkanna, Ganesan Sathiyanarayanan, Amit Kumar Rai, Krishnamurthy Mathivanan, Kandasamy Saravanan, Kumaresan Sudharsan, Palanisamy Kalimuthu, Yongkun Ma and Soundarapandian Sekar, 2022. Exopolysaccharide produced by probiotic Bacillus albus DM-15 isolated from Ayurvedic fermented Dasamoolarishta: Characterization, antioxidant and anticancer activities, Frontiers in Microbiology, doi: 10.3389/fmicb.2022.832109. Impact Factor: 4.5
  • Mathivanan, Krishnamurthy, Jayaraman Uthaya Chandirika, Annadurai Vinothkanna, Huaqun Yin, Xueduan Liu, and Delong Meng, 2021. Bacterial adaptive strategies to cope with metal toxicity in the contaminated environment–A review. Ecotoxicology and Environmental Safety, 226, 112863. Impact Factor: 6.1
  • Hu, Jie, Annadurai Vinothkanna, Meng Wu, John‐Nelson Ekumah, Nelson Dzidzorgbe Kwaku Akpabli‐Tsigbe, and Yongkun Ma, 2021. Tracking the dynamic changes of a flavor, phenolic profile, and antioxidant properties of Lactiplantibacillus plantarum‐and Saccharomyces cerevisiae‐fermented mulberry wine. Food Science & Nutrition 9(11), 6294-6306. Impact Factor: 3.8
  •  Ishak KS, Panneerselvam A, Ambikapathy V, Sathya R, Vinothkanna A, 2021. An investigation of sewage water treatment plant and its physico-chemical analysis. Biocatalysis and Agricultural Biotechnology. 1;35, 102061. Impact Factor: 3.8
  • Thasma Raman Sivakumar, Duraiarasan Surendhiran, Keping Chen, Peng Lv, Annadurai Vinothkanna, Ragothaman Prathiviraj, Sivasamy Sethupathy, Abdul Razack Sirajunnisa 2021. Network pharmacology-based analysis of Astragalus propinquus components for the treatment of rheumatoid arthritis and diabetes, South African Journal of Botany. 139, 92-105. Impact Factor: 2.7
  • Annadurai Vinothkanna, Ganesan Sathiyanarayanan, Perumalsamy Balaji, Krishnamurthy Mathivanan, Arivalagan Pugazhendhi, Yongkun Ma, Soundarapandian Sekar, Ramasamy Thirumurugan, 2021. Structural characterization, functional and biological activities of an exopolysaccharide produced by probiotic Bacillus licheniformis AG-06 from Indian polyherbal fermented traditional medicine. International Journal of Biological Macromolecules. 174, 144-152.
  • Impact Factor: 8.5
  • Krishnamurthy Mathivanan, Jayaraman Uthaya Chandirika, Annadurai Vinothkanna, R. K. Govindarajan, Delong Meng and Huaqun Yin, 2021. Characterization and Biotechnological Functional Activities of Exopolysaccharides produced by Lysinibacillus fusiformis KMNTT-10. Journal of Polymers and the Environment, pp.1-10.
  • Impact Factor: 5.0
  • Pushparaj Annadurai, Vinothkanna Annadurai, Yongkun Ma, Arivalagan Pugazhendhi, Kandavel Dhandayuthapani, 2021. Phytochemical composition, antioxidant and antimicrobial activities of Plecospermum spinosum Trecul. Process Biochemistry, 100, pp.107-116. Impact Factor: 4.0
  • Krishnamurthy Mathivanan, Jayaraman Uthaya Chandirika, Thangavel Mathimani Annadurai Vinothkanna, Rajendran Rajaram, Gurusamy Annadurai, 2020. Optimization, compositional analysis, and characterization of exopolysaccharides produced by multi-metal resistant Bacillus cereus KMS3-1. Carbohydrate Polymers, 227, 115369. Impact Factor: 12.5
  • Selvamani, Karthikeyan, Annadurai Vinothkanna, and Soundarapandian Sekar, 2019. Improved co-composting of poultry manure with a complementary consortium of indigenous Bacillus spp. 3 Biotech, 9: 215.  Impact Factor: 2.9
  • Annadurai Vinothkanna, and Soundarapandian Sekar, 2019, Probiotic properties of intrinsic bacteria isolated from fermented polyherbal preparations of Indian Ayurveda. LWT- Food Science and Technology, 103, 8-18. Impact Factor: 6.6
  • Soundarapandian Sekar, and Annadurai Vinothkanna, 2019, Polyherbal and submerge fermented medicines of Ayurveda: Convergence of tradition with scientific trends and needs. South African Journal of Botany, 21, 410-417. Impact Factor: 2.7
  • Annadurai Vinothkanna, Palanisamy Premkumar, and Soundarapandian Sekar, 2019, Activity of antibacterial compounds from Bacillus subtilis against cellular oncoproteins by in silico approach. Biocatalysis and Agricultural Biotechnology, 18, 101059. Impact Factor: 3.8
  • Annadurai Vinothkanna, and Soundarapandian Sekar, 2018, Influence of intrinsic microbes on phytochemical changes and antioxidant activity of the Ayurvedic fermented medicines: Balarishta and Chandanasava. AYU (An International Quarterly Journal of Research in Ayurveda), 39 (3), 169-181. (PubMed indexed)
  • Annadurai Vinothkanna, Bagavathy Shanmugam Karthikeyan., Ramachandran Vijayan & Soundarapandian Sekar. (2018). Assessment of anti-arthritic potential of traditionally fermented ayurvedic polyherbal product chandanasava by molecular modeling, docking and dynamics approaches. International Journal of Computational Biology and Drug Design, 11(4), 346-368. (Scopus indexed)
  • Annadurai Vinothkanna, and Sekar Soundarapandian, 2018, Antioxidant Activity of Fermented Traditional Medicines of Indian Ayurveda – Ashokarishta, Aswagandharishta and Dasamoolarishta. Biosciences Biotechnology Research Asia, 15(3), 699-709. (Scopus indexed)
  • Ilayaperumal Pradeep, Balagurusamy Balajothi, Sankaralingam Arunachalam, Rajakumar Dhivya, Annadurai Vinothkanna, Mohammad Abdulkadher Akbarsha and Soundarapandian Sekar, 2016, “Fluorescent active ruthenium (II) complex units containing bpy or phen or dmp ligands anchored on branched poly (ethylenimine): DNA binding and in vitro biological assessment. RSC Advances, 6(38), 31831-31839. Impact Factor:  4.6
  • Dharmaraj Ramesh, Annadurai Vinothkanna, Amit Kumar Rai Venkada Subramanian Vignesh, 2015. Isolation of potential probiotic Bacillus spp. and assessment of their subcellular components to induce immune responses in Labeo rohita against Aeromonas hydrophila. Fish & Shellfish Immunology, 45(2), 268-276. Impact Factor: 3.9
  • Annadurai Vinothkanna, Paramasivam Manivannan, Gangatharan Muralitharan G and Soundarapandian Sekar (2014), In silico probing of anti-arthritic potential of traditionally fermented ayurvedic polyherbal product Balarishta reveals lupeol and desulphosinigrin as efficient interacting components with UreC. International Journal of Pharmacy and Pharmaceutical Sciences, 6, 469-475. Scopus Indexed
  • Annadurai Vinothkanna, Subbiah Mariappan, and Soundarapandian Sekar, 2014, Tracking the organoleptic and biochemical changes in the ayurvedic polyherbal and native fermented traditional medicines: Balarishta and Chandanasava. International Journal of Pharmacy and Pharmaceutical Sciences, 6(9) (2014): 521-26, Scopus Indexed
  • Ilayaperumal Pradeep, Megarajan, S, Sankaralingam Arunachalam, Rajakumar Dhivya, Annadurai Vinothkanna, Mohammad Abdulkadher Akbarsha and Soundarapandian Sekar, (2014), Ferrocenyl methylene units and copper (ii) phenanthroline complex units anchored on branched poly (ethyleneimine)–DNA binding, antimicrobial and anticancer activity. New Journal of Chemistry, 38(9) 4204-4211. Impact Factor: 2.5
  • Ganesan Sathiyanarayanan, Venkatasamy Vignesh, Ganesan Saibaba, Annadurai Vinothkanna, Krishnamoorthy Dineshkumar, Madepalli Byrappagowdu Viswanathanan and Joseph Selvin, (2014), Synthesis of carbohydrate polymer encrusted gold nanoparticles using bacterial exopolysaccharide: a novel and greener approach. RSC Advances, 4(43), 22817-22827. Impact Factor: 4.6

BOOK CHAPTERS PUBLSIHED

  • Annadurai Vinothkanna and Soundarapandian Sekar, (2020) Diagnostic Applications of Phycobiliproteins. In: Jacob-Lopes E., Queiroz M., Zepka L. (eds) Pigments from Microalgae Handbook. Springer, Cham. https://doi.org/10.1007/978-3-030-50971-2_24.
  • Annadurai Vinothkanna*, Jia Aiqun and Yanan Gao* “Protease antibacterial materials” (2025). In: En-Tang Kang and Liqun Xu"Antimicrobial Materials and Interfaces: Synthesis, Characterization, and Applications, ISBN 978-3-527-35382-8, Wiley-VCH.

NCBI NUCLEOTIDE SUBMISSIONS - 34

  • Bacillus and Yeast spp. from Ayurvedic fermented medicines and poultry waste: MH006572 - MH006575; KP859547 - KP859558; KJ562355 & KJ562356; KJ854384 - KJ854386; KJ620420 - KJ620425 and MW031905.
  • Yeast spp. from natural resources: MW534716, MW534718, MW534720, MW534721, MW534722 and MW534726.
  • Industry—Academia Light Microscopy Workshop, “From Basics to Optical Sectioning,” organized by Carl Zeiss India (Bangalore) Pvt. Ltd. in association with the National Centre for Alternatives to Animal Experiments, was held on 14th and 15th May 2018.
  • A national-level lecture workshop on “Plant Tissue Culture and Phytochemistry” was organized by the Department of Botany, Bharathidasan University, Tiruchirappalli-24, on 21 March 2018.
  • The “International Conference on Environment and Health in Changing Climate” was organized by the Bharathidasan University, Tiruchirappalli-24, and held from 14 to 16 September 2016.
  • “Antibiotic Resistance Awareness Programme” organized by the Department of Microbiology, Bharathidasan University, Tiruchirappalli-24 and Indian Initiative for Management of Antibiotic Resistance, Ujjani held on 15th Nov - 2015.
  • The “Two-Day Workshop on Computer-Aided Drug and Biologics Discovery” (Hands-on Training in the Schrodinger in HPC facility @ UIC) was organized by the University Informatics Centre, Bharathidasan University, Tiruchirappalli-24, and held on November 16th and 17th, 2015.
  • “A 5–day Training Programme on Research Writing: Elements and Steps” organized by the Centre for Technical and Academic Writing, Bharathidasan University, Tiruchirappalli-24 held on 16th to 20th Feb 2015.
  • One-day “Biotechnology Based Entrepreneurship Awareness” seminar organized by the Department of Industrial Biotechnology, Bharathidasan University, Tiruchirappalli-24 held on 22nd Jan 2015.
  • “Writing Science – One-day seminar on Scientific / Technical Writings” organized by the Department of Industrial Biotechnology, Bharathidasan University, Tiruchirappalli-24 held on January 22nd, 2014.
  • National Conference on “Marine Environmental Challenges and Coastal Zone Management Strategy” organized by the Department of Marine Science, Bharathidasan University, Tiruchirappalli-24, held on 13th and 14th February 2012.
  • “International Symposium on Trace Organic Pollutants in the Environment” organized by the Department of Environmental Biotechnology, Bharathidasan University, Tiruchirappalli-24, held on 23rd January 2010.
  • Biovision09 workshops on “Advanced Techniques on Molecular Biology” were jointly organized by the Genome Park Chennai on 22 and 23 August 2009.
  • Foreign High Talent E, awarded by Hainan Province, Haikou, PR, China (October 2023)
  • Chinese Government Post-Doctoral Fellowship, Post-Doctoral Researcher awarded by Hainan University, PR, China (May 2023)
  • Chinese Government Post-Doctoral Fellowship, Post-Doctoral Researcher awarded by Jiangsu University, PR, China (May 2019).
  • Foreign Young Talents Program, Foreign Expert, awarded by the Ministry of Science and Technology, PR, China, (February 2020).
  • National Fellowship, awarded by University Grants Commission (UGC), Government of India, (April 2016).
  • University Research Fellowship (URF) awarded by the Department of Biotechnology, Bharathidasan University, Tamil Nadu, India (July 2013).

Research Enrichment Contributions as a Reviewer

  • Carbohydrate Polymer Technologies and Applications (Elsevier)
  • Journal of Food Processing and Preservation (Wiley)
  • Food Bioscience (Elsevier)
  • International Journal of Biological Macromolecules (Elsevier)
  • Journal of Advanced Research (Elsevier)
  • Polymers for Advanced Technologies (Wiley)
  • Frontiers in Pharmacology
  • Frontiers in Microbiology
  • BMC – Microbiology (Springer Nature)
  • Phytomedicine (Elsevier)
  • International Nano Letters (Springer Nature)
  • Journal of Herbal Medicine (Elsevier)
  • Scientific Reports (Springer Nature)
  • Journal of Ayurveda and Integrative Medicine (Elsevier)
  • Biocatalysis and Agricultural Biotechnology (Elsevier)
  • Heliyon (Elsevier)
  • Arabian Journal of Chemistry (Elsevier)
  • Applied Biochemistry and Biotechnology (Springer Nature)
  • Natural Product Communications (SAGE)
  • Journal of Plant Diseases and Protection (Springer Nature)

Research Enrichment Contributions as a Guest Editor

  • Serving as a Guest Editor for Frontiers in Pharmacology under the title "Polyphenolic Compounds in Combatting MDR Pathogens: Current Research and Future Directions" (https://loop.frontiersin.org/people/1456026/editorial).