Admissions 2023

Department of Biosciences

Dr. Rajiv Gandhi Gopalsamy

Designation : Scientist D

Qualification : Ph.D

Email-ID : rgandhi@rajagiri.edu

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  • Post doctorate research internship specializations in Health Sciences From Federal University of Sergipe, Aracaju, Brazil
  • Doctor of Philosophy specializations in Biochemistry Loyola College, University of Madras, India
  • Master of Philosophy specializations in Biochemistry Bharathidasan University, Trichy, India
  • Postgraduate Diploma in Herbal Technology (PGDHT) Bharathidasan University, Trichy, India
  • Master of Science specializations in Biochemistry Bharathidasan University, Trichy, India
  • Bachelor of Science specializations in Biochemistry St Joseph’s College, Cuddalore, University of Madras, India
  • Senior Research Fellow (SRF) Council of Scientific and Industrial Research: Loyola College, Chennai, India (April 2012- March 2015)
  • Post-doctoral researcher: Department of Health Sciences, Federal University of Sergipe, University Hospital, Aracaju, Brazil (January 2016- December 2016)
  • Research Scientist Level I: Department of Health Sciences, Federal University of Sergipe, University Hospital, Aracaju, Brazil (January 2017- December 2018)
  • Assistant Research Professor, Department of Health Sciences, Postgraduate Program in Health Sciences, University Hospital, Aracaju, Brazil (February 2018 – January 2021)
  • Research Scientist Level II: Department of Health Sciences, Federal University of Sergipe, University Hospital, Aracaju, Brazil (January 2019- December 2020)
  • Research Scientist Level III: Department of Physiology and Pharmaceutical Sciences (DFS/UFS), Sao Cristavao Campus, Brazil (January 2021 – December 2021)
  • Phytochemistry
  • Drug Design
  • Pharmaceutics
  • Toxicology
  • Pharmacology
  • Phytomedicine
  • Molecular Biology
  • Food and Nutrition
  • CNPQ, Federal Government of Brazil project titled “Chemopreventive efficacy of orange peel extract and its lead molecule rosmarinic acid in experimental colon cancer via targeting NF-kappa B signaling pathway”. Value Indian Rupees. 95.5 lakhs. Role: Research Scientist III. Duration: 2021.
  • CAPES, Federal Government of Brazil project titled “The use of cyclodextrin inclusion complexes to enhance the therapeutic efficacy of anticancer drug profiles”. Value Indian Rupees. 75.5 lakhs. Role: Research Scientist II. Duration: 2019-2020.
  • CAPES, Federal Government of Brazil project titled “Evidence of insulin dependent signaling mechanisms by Citrus sinensis (L.) Osbeck fruit peel in insulin resistant rats”. Value Indian Rupees. 55.5 lakhs. Role: Research Scientist I. Duration: 2017-2018.
  • CNPQ, Federal Government of Brazil project titled “In vitro and in vivo antirotaviral activity of Citrus sinensis (L.) Osbeck fruit peel with mechanism of action”. Value Indian Rupees. 29.5 lakhs. Role: Individual Post-doctoral researcher. Duration: 2016
  • CSIR, Government of India funded Senior Research Fellowship project titled “Isolation, identification and mechanism of action of antidiabetic lead molecule from Cyamopsis tetragonoloba L. Taub bean”. Value Indian Rupees. 9.25 lakhs. Role: Individual Senior Research Fellow. Duration: 2012-2015
  • G R Gandhi, P J Antony, M J M P Lana,  B F X Silva, R V Oliveira, G Jothi,  G Hariharan, T Mohana, R Y Gan,  R Q Gurgel, R Cipolotti, L J Q Junior, Natural products modulating interleukins and other inflammatory mediators in tumor-bearing animals: a systematic review. Phytomedicine (Impact factor: 5.34) (ISSN: 0944-7113) March 2022, 154038, DOI: https://doi.org/10.1016/j.phymed.2022.154038
  • G R Gandhi, H Li, A B S Vasconcelos, M M Montalvão, M N F Franca, X He, P Rong, H B Li, R Y Gan, Bioactive constituents and potential health benefits of fermented seed products. In book: Indigenous Fermented Foods for the Tropics (In press), January 2022, Book edited by.  Prof. Oluwafemi Adebo, Professor in food technology University of Johannesburg. Chapter 27.
  • G R Gandhi, G Jothi, T Mohana, A B S Vasconcelos, M M Montalvão, G Hariharan, G Sridharan, P M Kumar, R Q Gurgel, H Li, J Zhang, R Gan, Anti-inflammatory natural products as potential therapeutic agents of rheumatoid arthritis: A systematic review. Phytomedicine (Impact factor: 5.34) (ISSN: 0944-7113) September 2021, 153766, DOI: https://doi.org/10.1016/j.phymed.2021.153766
  • N B Macedo, D D Gutierrez, A S Santos, R O Pereira, G R Gandhi, M G OSilva, A Vidal, L J Q Júnior, J S S Quintans, A M O Silva, Bioactive compounds from Schinus terebinthifolius Raddi and their potential health benefits. In book: Phytopharmaceuticals (pp. 363-402), May 2021, DOI: 10.1002/9781119682059. ch20
  • F J Lin, X L Wei, H Y Liu, H Li, Y Xia, D T Wu, P Z Zhang, G R Gandhi, HB Li, R Y Gan. State-of-the-art review of dark tea: From chemistry to health benefits. Trends in Food Science & Technology (Impact factor: 12.563) (March, 2021) 109: 126-138. DOI https://doi.org/10.1016/j.tifs.2021.01.030
  • G R Gandhi, A B S Vasconcelos, D Wu, H Li, P J Antony, H Li, F Geng, R Q Gurgel, N Narain, R Y Gan. Citrus flavonoids as promising phytochemicals targeting diabetes and related complications: A systematic review of in vitro and in vivo studies. Nutrients (Impact factor: 5.717) (September, 2020) 12 (10): 2907, Article ID: 926667 DOI 10.3390/nu12102907
  • S R Gandhi, J S S Quintans, G R Gandhi, L J Q Júnior, R Q Gurgel. The use of cyclodextrins inclusion complexes to improve anti-cancer drug profiles - A systematic review. Expert Opinion on Drug Delivery (Impact factor: 6.640) (May, 2020) 17: 1069-1080. DOI https://doi.org/10.1080/17425247.2020.1776261
  • G R Gandhi, A B S Vasconcelos, G C S Leão, M L D Almeida, G Sridharan, G Jothi, T Mohana, N Narain , R Q Gurgel. Flavonoids as cytokine immunomodulators to reduce airway inflammation via inhibition of the NF-κB signalling pathway: A systematic overview. In: eLS. John Wiley & Sons, Ltd: Chichester. DOI: 10.1002/9780470015902.a0028888
  • G R Gandhi, G C S Leão, V K S Calisto, A B S Vasconcelos, M L D Almeida, J S S Quintans, E Barreto, N Narain, L J Q Júnior, R Q Gurgel. Modulation of interleukin expression by medicinal plants and their secondary metabolites: a systematic review on anti-asthmatic and immunopharmacological mechanisms. Phytomedicine (Impact factor: 5.34) (ISSN: 0944-7113) (April, 2020) 70: 153229) DOI 10.1016/j.phymed.2020.153229.
  • G R Gandhi, A B S Vasconcelos, G H Haran, V K D S Calisto, G Jothi, J S S Quintans, L E Cuevas, N Narain, L J Q Júnior, R Cipolotti, R Q Gurgel. Essential oils and its bioactive compounds modulating cytokines: A systematic review on anti-asthmatic and immunomodulatory properties. Phytomedicine. (January, 2019) Article ID, 152854. (Impact factor: 5.34) (ISSN: 0944-7113) DOI 10.1016/j.phymed.2019.152854
  • G R Gandhi, M T S L Neta, R G Sathiyabama, J S  Siqueira Quintans, A M O E Silva,  A A S Araújo,  N Narain,  L J  Quintans-Júnior,  R Q Gurgel. Flavonoids as Th1/Th2 cytokines immunomodulators: A systematic review of studies on animal models, Phytomedicine (Stuttgart).   (May, 2018) 15: 74-84. (Impact factor: 5.34) (ISSN: 0944-7113) DOI 10.1016/j.phymed.2018.03.057
  • R G Sathiyabama,  G R Gandhi, M Denadai, G Sridharan, G Jothi, P Sasikumar,  J S Siqueira Quintans,  N Narain,  L E Cuevas,  H D M Coutinho,  A G B Ramos,  L J Quintans-Júnior,  R Q Gurgel. Evidence of insulin-dependent signaling mechanisms produced by Citrus sinensis (L.) Osbeck fruit peel in an insulin resistant diabetic animal model. Food and Chemical Toxicology (July, 2018) 116: 86-99. (Impact factor: 6.023) (ISSN: 0278 - 6915) DOI 10.1016/j.fct.2018.03.050
  • G R Gandhi, V S Santos, M Denadai, V K D S Calisto, J S S Quintans, A M D Silva, A A S Araújo, N Narain, L Cuevas, L J Q Júnior, R Q Gurgel. Cytokines in the management of rotavirus infection: A systematic review of in vivo studies. Cytokine. (May, 2017) 96: 152-160. (Impact factor: 3.861) (ISSN: 1043-4666) DOI 10.1016/j.cyto.2017.04.013
  • P J Antony, G R Gandhi, A Stalin, K Balakrishna, E Toppo,  K Sivasankaran,  S Ignacimuthu, N A Al-dhabi. Myoinositol ameliorates high-fat diet and streptozotocin-induced diabetes in rats through promoting insulin receptor signaling. Biomedicine & pharmacotherapy. (February, 2017) 88: 1098-1113. (Impact factor: 6.529) (ISSN: 0753-3322) DOI 10.1016/j.biopha.2017.01.170.
  • G R Gandhi, P G Barreto, B S Lima, J S S Quintans, A A S Araújo, N Narain, L J Q Júnior, R Q Gurgel. Medicinal plants and natural molecules with in vitro and in vivo activity against rotavirus: A systematic review. Phytomedicine (Stuttgart).  (November, 2016) 23: 1830-1842. (Impact factor: 5.34) (ISSN: 0944-7113) DOI 10.1016/j.phymed.2016.11.005.
  • J C Silva, J R G S. Almeida, J S S Quintans, G R Gandhi, S Shanmugam, M R Serafini, M R C Oliveira, B A F Silva, A O B P B Martins, F F Castro, I R A Menezes, H D M Coutinho, R C M Oliveira, P Thangaraj, A A S Araújo, L J Quintans-Júnior. Enhancement of orofacial antinociceptive effect of carvacrol, a monoterpene present in oregano and thyme oils, by β-cyclodextrin inclusion complex in mice. Biomedicine and Pharmacotheraphy (September, 2016) 84: 454-461. (Impact factor: 6.529) (ISSN: 0753-3322) DOI 10.1016/j.biopha.2016.09.065
  • A Stalin, S S Irudayaraj, G R Gandhi, K Balakrishna, S Ignacimuthu, N A Al-Dhabi. Hypoglycemic activity of 6-bromoembelin and vilangin in high-fat diet fed streptozotocin-induced type 2 diabetic rats and molecular docking studies. Life Sciences (May, 2016) 153: 100-117. (Impact Factor: 5.037) (ISSN: 0024 -3205) DOI  10.1016/j.lfs.2016.04.016.
  • G R Gandhi, G Jothi, P J Antony, K Balakrishna, M G Paulraj, S Ignacimuthu, A Stalin, N A Al-Dhabi. Gallic acid attenuates high-fat diet fed-streptozotocin-induced insulin resistance via partial agonism of PPARγ in experimental type 2 diabetic rats and enhance glucose uptake through translocation and activation of GLUT4 in PI3K/p-Akt signaling pathway. European Journal of Pharmacology (December, 2014), 745: 201-216. (Impact Factor: 4.432) (ISSN: 0014 - 2999)DOI 10.1016/j.ejphar.2014.10.044
  • G R Gandhi, P Vanlalhruaia, A Stalin, S S Irudayaraj, S Ignacimuthu, M G Paulraj. Polyphenols-rich Cyamopsis tetragonoloba (L.) Taub. beans show hypoglycemic and β-cells protective effects in type 2 diabetic rats. Food and Chemical Toxicology (April, 2014), 66: 358-365. (Impact Factor: 6.023) (ISSN: 0278 - 6915) DOI 10.1016/j.fct.2014.02.001. 
  • G R Gandhi, A Stalin, K Balakrishna, S Ignacimuthu, M G Paulraj, R Vishal. Insulin sensitization via partial agonism of PPARγ and glucose uptake through translocation and activation of GLUT4 in PI3K/p-Akt signaling pathway by embelin in type 2 diabetic rats. Biochimica et Biophysica Acta - General Subjects (January, 2013), 1830: 2243-2255. (Impact Factor: 3.77) (ISSN: 0304 - 4165) DOI 10.1016/j.bbagen.2012.10.016.
  • G R Gandhi, S Ignacimuthu, M G Paulraj. Hypoglycemic and β-cells regenerative effects of Aegle marmelos (L.) Corr. bark extract in streptozotocin-induced diabetic rats, Food and Chemical Toxicology (May, 2012), 50:1667-1674. (Impact Factor: 6.023) (ISSN: 0278 - 6915) DOI 10.1016/j.fct.2012.01.030
  • R Vidhya, G R Gandhi, G Jothi, J Radhika, P Brindha. Evaluation of antidiabetic potential of Achyranthes aspera Linn. on alloxan induced diabetic animals. International Journal of Pharmacy and Pharmaceutical Sciences (2012), 4, 577-580. (ISSN:  0975 - 1491)
  • G R Gandhi, P Sasikumar. Antidiabetic effect of Merremia emarginata Burm. F. in streptozotocin induced diabetic rats. Asian Pacific Journal of Tropical Biomedicine (April, 2012), 2, 281-286. (Impact Factor: 1.587) (ISSN: 2221-1691) DOI 10.1016/S2221-1691(12)60023-9
  • G R Gandhi, S Ignacimuthu, M G Paulraj. Solanum torvum Swartz. fruit containing phenolic compounds shows antidiabetic and antioxidant effects in streptozotocin-induced diabetic rats, Food and Chemical Toxicology (November, 2011), 49:2725 - 2733. (Impact Factor: 6.023) (ISSN: 0278 - 6915) DOI 10.1016/j.fct.2011.08.005.
  • G R Gandhi, S Ignacimuthu, M G Paulraj, P Sasikumar. Antihyperglycemic activity and antidiabetic effect of methyl caffeate isolated from Solanum torvum Swartz. fruit in streptozotocin-induced diabetic rats. European Journal of Pharmacology (November, 2011), 670:623- 631. (Impact Factor: 4.432) (ISSN: 0014 - 2999) DOI 10.1016/j.ejphar.2011.09.159.
  • Underwent the adhoc training course on “Laboratory Animal Sciences” at National Centre for Laboratory Animal Sciences, National Institute of Nutrition, Hyderabad, India from March 8-13, 2010.
  • Attended the short-term training course on “Methods in in vitro Toxicology” at MGDC, Bharathidasan University, Trichy, India from October 2-11, 2010.
  • Participated in “2nd Biennial International conference on new developments in drug discovery from natural products and traditional medicines” held from 20-24 November, 2010 at National Institute of Pharmaceutical Education and Research, Punjab, India.
  • Presented a research paper in the National conference on “Phytomedicine” held at Bharathiar University, Coimbatore during October 4-5, 2012.
  • Presented a research paper in the National conference on “Phyto drugs and Human Healthcare” held at Anna University Regional Centre, Coimbatore during August 22-23, 2013.
  • Short term certificate course in Molecular Diagnostics
  • Short term certificate course in Recent Advancements in Transgenic Technology
  • Post Graduate Diploma in Hospital Administration
  • Awarded PDJ fellowship by CNPq (Brazil) for the period February 2021- December 2021
  • Assigned as Research Assistant Professor at Postgraduate program in Health Sciences (PPGCS), Federal University of Sergipe, Aracaju, Brazil for the period February 2018- January 2021 
  • Awarded PDS Internship by Programa Nacional de Pós Doutorado da CAPES (PNPD/CAPES), Brazil for the period February 2019 - January 2021.
  • Distinguished Speaker at International conference on cardiology (October 26-27, 2016) held at Federal University of Sergipe, Aracaju, Brazil 
  • Awarded Senior Research Fellowship (SRF) by Council of Scientific and Industrial Research (CSIR), Government of India for the period 2012-2015.
  • Obtained the research grant from DBT (Department of Biotechnology), for attending the short-term training course on “Bioprospecting of Medicinal Plants: A Biotechnological Approach” held at Department of Botany, Bharathiar University, Coimbatore, India for the period of 15 days during February 2012.  
  • Obtained the research grant from UGC (University Grants Commission), for attending the short-term summer training course on “Advanced Biochemistry and Molecular Diagnostic techniques” held at UGC-NRCBS, Madurai Kamaraj Universiy, Madurai, India for 21 days during June 2010.
  • Secured University Rank VIII in M.Sc Biochemistry among non-autonomous    colleges at Bharathidasan University for the academic year 2005-2007.
  • Secured University Rank XIX at M.Sc Biochemistry among non-autonomous    colleges and autonomous colleges in Bharathidasan University for the academic year 2005-2007.
  • Federal University of Sergipe, Aracaju, Brazil (as a Postdoctoral researcher and Research Scientist)
  • Institute of Urban Agriculture, Chinese Academy of Agricultural Sciences, Chengdu, China (as a Visiting Scientist and Collaborator)
  • St. Xavier’s college, Kathmandu, Nepal (Collaborator)
  • Beijing-Normal University-Hong Kong Baptist University, United International College, Beijing, China (Collaborator)
  • University of Johannesburg, South Africa (Collaborator) 

Industrial Visits on Research and trainings

  • SPIC Pharmaceuticals Private Limited, (Penicillin-G productions) at Cuddalore, India (June 2006)
  • E.I.D Parry’s (India) Limited, (Sugar refineries) at Cuddalore, India (September 2006)
  • Asian Paints (India) Limited, (Painting Chemicals) at Cuddalore, India (December 2006)
  • Shasun Drugs and Chemicals Limited, (Drug Product Developments) at Cuddalore, India (February 2007)
  • Trichy Distilleries and Chemicals Limited, (Chemicals and Dyes) at Trichy, India (May 2007)
  • Neyveli Lignite Corporation Limited (Centre for Applied Research and Development) at Neyveli, India (June 2007)
  • Tamilnadu Newsprint and Paper Limited (TNPL), (Paper Manufactures) at Karur, India (October 2007)
  • Aavin Milk, (Dairy Products) at Trichy, India (January 2008)
  • Ad hoc Reviewer for the manuscripts from Food and Chemical Toxicology, Frontiers in Nutrition, Journal of Herbal Medicine, Phytomedicine, Pharmaceutical Biology